Advair Lawsuit | Advair Inhaler Asthma-Related Death Lawsuit | Life-Threatening Side Effects
Advair Lawsuit | Lawsuits, Lawyer, Attorney | Advair Inhaler Asthma-Related Death Lawsuit | Life-Threatening Side Effects | Advair Black Box Warning
The leading law firm of Alonso Krangle LLP is investigating asthma-related deaths and Advair lawsuits associated with the use of Advair. Advair contains the active ingredient salmeterol, a long acting beta agonist (LABAs). In 2010, the U.S. Food & Drug Administration (FDA) warned that LABAs had been associated with severe exacerbation of asthma symptoms, sometimes leading to the hospitalization of both children and adults. At the time, the FDA also reported that LABA-containing drugs, including Advair, had been associated with asthma-related deaths in some patients.
If you lost a loved one, including a child, to an asthma-related death caused by Advair, nothing can make up for that. The defective drug injury lawyers at Alonso Krangle LLP understand this, but also know that it is important to hold pharmaceutical companies accountable when they fail to warn patients about potentially life-threatening side effects that may be linked to their drugs. Filing an Advair lawsuit or Advair asthma-related death lawsuit is one way to hold GlaxoSmithKline accountable for the pain, suffering and emotional distress inflicted on your family by Advair. The defective drug lawyers at Alonso Krangle LLP are currently offering FREE Advair lawsuit consultations to anyone injured by Advair, and their families, in all 50 states. To learn more about the legal options at your disposal and an Advair lawsuit, please contact the Advair side effect lawyers at Alonso Krangle LLP today.
Advair and Worsening Asthma Symptoms, Asthma-Related Death
Advair is a combination of a drug called fluticasone and the LABA salmeterol that are supposed to help prevent asthma attacks. Advair is sold in an inhaler form (Advair HFA), which is approved for patients with asthma. Asthma Diskus is approved for patients with asthma, as well as adults with chronic obstructive pulmonary disease (COPD), including chronic bronchitis, emphysema, or both.
LABA’s work by relaxing muscles in the airway and lungs. This helps patients breathe easier, and lessens symptoms such as wheezing and shortness of breath. LABA’s are used for asthma control, not for sudden onset of symptoms. Other LABA medications include Symbicort, Serevent and Foradil.
Advair Black Box Warning : Black Box Warning To Heighten Awareness Of An Increased Risk Of Death
Since at least 2005, LABAs have been linked to an increased risk of worsening asthma and asthma-related deaths. That year, GlaxoSmithKline agreed to revise a “black-box” warning on its Advair and Serevent LABA medications to further heighten awareness of an increased risk of death associated with salmeterol. The modified warning cautioned doctors and patients that salmeterol may increase the risk of asthma-related death.
In June 2006, a study published in the Annals of Internal Medicine found that the rate of asthma patients being hospitalized was double for users of these medications. The meta-analysis examined 19 trials and 33,826 asthma patients who took either the long-acting bronchodilators or placebos. The analysis found that people on LABAs were 4 to 6 times more likely to die of asthma-related causes than those on placebo.
In February 2010, the FDA warned that LABAs, including Advair, should only be taken in conjunction with an inhalable steroid. According to the agency, patients using an LABA alone have an increased risk of hospitalization and death due to exacerbated asthma symptoms. The new warning only applied for people who used Advair and other LABAs for asthma control, not as a treatment for COPD. Even though Advair does contain a corticosteroid, the FDA said an inhalable steroid should still be used along with Advair.
The FDA also recommended that:
- Advair and other LABAs should be used long-term only in patients whose asthma cannot be adequately controlled on steroids alone.
- Advair and other LABAs should be used only for the shortest period of time required to achieve control of asthma symptoms and then discontinued.
- Children should use a combination product such as Advair or Symbicort to ensure that they receive both classes of drugs.
Legal Help for Victims of Advair Asthma-Related Deaths
If someone you love suffered an asthma-related death while using Advair, you may be eligible to file a product liability lawsuit against GlaxoSmithKline. To discuss your case with the Advair asthma death and injury lawyers at Alonso Krangle LLP, please fill out our online form, or call 1-800-403-6191.