Prilosec Birth Defects Lawsuit
The leading law firm of Alonso Krangle LLP is currently investigating potential legal claims on behalf of victims of birth defects associated with the proton pump inhibitor, Prilosec (omeprazole). Two studies have found a possible association between birth defects and drugs like Prilosec. Though more research is needed to confirm the connection between proton pump inhibitors, like Prilosec, and birth defects, this research is disturbing because so many women take proton pump inhibitors during pregnancy to control heart burn.
If you would like to investigate whether you have a case involving your use of Prilosec, please contact our lawyers at Alonso Krangle. We have the experience necessary to conduct a review of your potential case, see if a Prilosec lawsuit is warranted and give you the personalized attention that you deserve. The defective drug lawyers at Alonso Krangle LLP are currently offering free lawsuit consultations in all 50 states to any family who believes Prilosec caused their baby’s birth defect. To learn more about obtaining justice for your child, please contact the Prlosec birth defect lawyers at Alonso Krangle today.
Prilosec and Birth Defects
The U.S. Food & Drug Administration (FDA) approved AstraZeneca’s Prilosec in 1989, and it was the first proton pump inhibitor to come to market. Prilosec is also available as an over-the-counter medication, Prilosec OTC.
Prilosec was approved to decrease the amount of stomach acid created by the body, in order to reverse the side effects of Gastroesophageal Reflux Disease (GERD or acid reflux disease). Prilosec is sometimes used off-label to treat ulcers, Zollinger-Ellison Syndrome, H. Pylori infection of the stomach, and laryngitis. Proton pump inhibitors, like Prilosec, work by blocking the production of stomach acid. They do this by shutting down a system in the stomach known as the proton pump.
Prilosec has been assigned to pregnancy category C by the U.S. Food & Drug Administration (FDA). Some animal studies have revealed evidence of embryolethality and fetotoxicity, meaning it may cause injury or death to an unborn baby. There are no controlled data in human pregnancy. Prilosec should only be prescribed to pregnant women if the benefits outweigh its risks.
In 2001, a small retrospective study of 955 pregnancies where the mother used Prilosec during pregnancy showed that five children were stillborn and overall there seemed to be an increased incidence of congenital heart defects. However, the author concluded “both effects may be random,” and few large studies have been conducted since then to evaluate the safety of PPIs in pregnancy. AstraZeneca quotes that statement on the Prilosec label to minimize the perception of the drug’s potential risk.
In 2010, two studies did raise concerns about the use of proton pump inhibitors in expectant mothers. The first, conducted at the University of Pennsylvania and published in the journal Gastroenterology, drew data on 200,000 pregnant women from the Health Improvement Network (THIN) database. The study found that taking proton pump inhibitors in early pregnancy was associated with a doubling in the risk of newborn cardiac birth defects, such as septal defect.
The second study, this time out of Denmark and published in the New England Journal of Medicine, suggested that the number of children with birth defects born to women taking proton pump inhibitors was not statistically significant. However, the same study also found that women who took the medications in the four weeks leading up to pregnancy had a 39 percent greater risk of having children with birth defects.
Learn More About Filing A Prilosec Birth Defect Lawsuit
If your child was born with a birth defect, and you believe Prilosec might be to blame, you may be eligible to file a lawsuit against the manufacturer of this medication. To learn more about the legal options available to you, please contact the Prilosec birth defect lawyers at Alonso Krangle LLP by filling out our online form or calling 1-800-403-6191.