Blood Clots

Blood Clot Side Effect (Thrombosis)

The medical term for a blood clot is a thrombus (plural= thrombi), and is the end result of the blood coagulation step in hemostasis. If the lining of the blood vessels becomes damaged, a blood clot forms via the aggregation of platelets that form a platelet plug. These activated platelets start the activation of the humoral coagulation system, using a series of clotting factors produced by the body. Ultimately, fibrin is formed, the protein that crosslinks with itself to form a mesh that makes up the final blood clot.

When a thrombus is formed as part of the normal clotting system to repair the body, there is little consequence. Unfortunately, there are times when a thrombus (blood clot) in an uninjured or slightly injured vessel. which can have potentially significant consequences. A thrombus in a large blood vessel will decrease blood flow through that vessel (termed a mural thrombus). In a small blood vessel, blood flow may be completely cut-off (termed an occlusive thrombus) resulting in death of tissue supplied by that vessel. If a thrombus dislodges and becomes free-floating, it is termed as an embolus.

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