Pancreatic cancer

Pancreatic Cancer

The pancreas a large gland that lies behind the stomach and next to the the first section of the small intestine called the duodenum. The pancreas aids in the digestion of carbohydrates, proteins, and fat by secreting a powerful digestive enzymes into the small intestine and regulate the bodies blood glucose metabolism by releasing the hormones insulin and glucagon into the bloodstream

Pancreatic cancer, even when diagnosed early often has an extremely poor prognosis. Pancreatic cancer typically spreads rapidly and is rarely detected in its early stages, which is a major reason why it’s the 4th most common cause of cancer-related deaths in the United States[1] and the eighth worldwide.[2] Signs and symptoms may not appear until pancreatic cancer is quite advanced and surgical removal isn’t possible.

Pancreatic cancer prognosis: for all the stages combined, the 1-year and 5-year relative survival rates are twenty-five percent-25% and six percent-6%, respectively;[3] for local disease the 5-year survival is approximately fifteen percent-15% [3][4] while the median survival for locally advanced and for metastatic disease, which collectively represent over eighty percent-80% of individuals,[4] is about 10 and 6 months respectively.

1- Hariharan, D.; Saied, A.; Kocher, H. M. (2008). “Analysis of mortality rates for pancreatic cancer across the world”. HPB 10 (1): 58–62. doi:10.1080/13651820701883148. PMC 2504856. PMID 18695761. edit

2- http://www.cancerresearchuk.org/cancer-info/cancerstats/world/the-global-picture/cancer-overall-world#source2

3- a b c d e f “American Cancer Society: Cancer Facts & Figures 2010: see page 4 for incidence estimates, and page 19 for survival percentages”.

4- a b c d National Cancer Institute. General Information About Pancreatic Cancer. http://www.cancer.gov/cancertopics/pdq/treatment/pancreatic/HealthProfessional

5- a b c d Benson AB, Myerson RJ, and Sasson AR. Pancreatic, Neuroendocrine GI, and Adrenal Cancers. Cancer Management 13th edition. http://www.cancernetwork.com/cancer-management/pancreatic/article/10165/1802606